INTERFERON ALFA-2A OR INTERFERON ALFA-2B: 402 Adverse Event Reports & Safety Profile

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402

Total FAERS Reports

61 (15.2%)

Deaths Reported

134

Hospitalizations

402

As Primary/Secondary Suspect

Life-Threatening

Disabilities

First Report: 19930329 · Latest Report: 20220222

What Are the Most Common INTERFERON ALFA-2A OR INTERFERON ALFA-2B Side Effects?

#1 Most Reported

Drug ineffective

56 reports (13.9%)

#2 Most Reported

Off label use

55 reports (13.7%)

#3 Most Reported

Neutropenia

23 reports (5.7%)

Side Effect	Reports	% of Total	Deaths	Hosp.
Drug ineffective	56	13.9%	6	8
Off label use	55	13.7%	6	18
Anaemia	23	5.7%	0	18
Neutropenia	23	5.7%	1	10
Fatigue	15	3.7%	2	7
Condition aggravated	14	3.5%	3	5
Headache	14	3.5%	0	2
Drug ineffective for unapproved indication	13	3.2%	1	8
Myelodysplastic syndrome	13	3.2%	8	1
Malignant neoplasm progression	12	3.0%	6	3
Pyrexia	12	3.0%	2	7
Thrombocytopenia	12	3.0%	0	3
Treatment failure	12	3.0%	0	0
Weight decreased	12	3.0%	2	9
Drug intolerance	11	2.7%	0	0
Nausea	11	2.7%	0	3
Haematotoxicity	10	2.5%	0	6
Asthenia	9	2.2%	2	5
Diarrhoea	9	2.2%	2	6
Disease progression	9	2.2%	3	1

Gender: 43.8% female, 56.2% male. Average age: 49.5 years. Most reports from: US. View detailed demographics →

Year	Reports	Deaths	Hosp.
2000	1	0	0
2003	5	3	1
2004	3	1	3
2005	1	0	0
2006	4	0	0
2008	6	2	6
2009	35	8	26
2010	30	3	29
2011	2	0	0
2012	3	1	1
2013	3	2	2
2014	13	3	9
2015	6	0	3
2016	8	0	8
2017	2	0	0
2018	3	0	0
2019	2	0	1
2020	11	2	2
2021	2	0	0
2022	1	0	1

Indication	Reports
Renal cell carcinoma	41
Chronic myeloid leukaemia	32
Product used for unknown indication	32
Covid-19	25
Hepatitis c	24
Plasma cell myeloma	15
Metastatic renal cell carcinoma	14
Renal cancer	13
Chronic hepatitis c	11
Malignant melanoma	11

Official prescribing information from the FDA-approved drug label.