Does ISONIAZID\PYRAZINAMIDE\RIFAMPIN Cause Jaundice? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Jaundice have been filed in association with ISONIAZID\PYRAZINAMIDE\RIFAMPIN. This represents 3.6% of all adverse event reports for ISONIAZID\PYRAZINAMIDE\RIFAMPIN.
15
Reports of Jaundice with ISONIAZID\PYRAZINAMIDE\RIFAMPIN
3.6%
of all ISONIAZID\PYRAZINAMIDE\RIFAMPIN reports
2
Deaths
14
Hospitalizations
How Dangerous Is Jaundice From ISONIAZID\PYRAZINAMIDE\RIFAMPIN?
Of the 15 reports, 2 (13.3%) resulted in death, 14 (93.3%) required hospitalization.
Is Jaundice Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID\PYRAZINAMIDE\RIFAMPIN. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID\PYRAZINAMIDE\RIFAMPIN Cause?
Hepatic cytolysis (50)
Drug reaction with eosinophilia and systemic symptoms (39)
Hepatocellular injury (37)
Cholestasis (32)
Thrombocytopenia (20)
Rash maculo-papular (19)
Rash (17)
Pyrexia (16)
Pruritus (15)
Mixed liver injury (14)
What Other Drugs Cause Jaundice?
RIBAVIRIN (647)
ACETAMINOPHEN (553)
ATORVASTATIN (518)
RIFAMPIN (336)
IBUPROFEN (334)
ECULIZUMAB (333)
METHOTREXATE (295)
OMBITASVIR\PARITAPREVIR\RITONAVIR (279)
AMOXICILLIN\CLAVULANATE (272)
DASABUVIR (247)
Which ISONIAZID\PYRAZINAMIDE\RIFAMPIN Alternatives Have Lower Jaundice Risk?
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISONIAZID\RIFAMPIN
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISOPROPANOLAMINE
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISOPROPYL ALCOHOL
ISONIAZID\PYRAZINAMIDE\RIFAMPIN vs ISOPROPYL ALCOHOL\LEUPROLIDE