Does IVACAFTOR Cause Bronchiectasis? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Bronchiectasis have been filed in association with IVACAFTOR (Kalydeco). This represents 0.2% of all adverse event reports for IVACAFTOR.
10
Reports of Bronchiectasis with IVACAFTOR
0.2%
of all IVACAFTOR reports
0
Deaths
9
Hospitalizations
How Dangerous Is Bronchiectasis From IVACAFTOR?
Of the 10 reports, 9 (90.0%) required hospitalization, and 1 (10.0%) were considered life-threatening.
Is Bronchiectasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IVACAFTOR. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does IVACAFTOR Cause?
Hospitalisation (1,209)
Infective pulmonary exacerbation of cystic fibrosis (550)
Infection (227)
Malaise (226)
Lower respiratory tract infection (224)
Pneumonia (215)
Death (203)
Cough (180)
Cystic fibrosis (167)
Headache (163)
What Other Drugs Cause Bronchiectasis?
PREDNISONE (1,169)
ALBUTEROL (1,026)
TIOTROPIUM (735)
BUDESONIDE\FORMOTEROL (684)
BUDESONIDE (573)
MEPOLIZUMAB (541)
CICLESONIDE (473)
MONTELUKAST (450)
ADALIMUMAB (420)
OMALIZUMAB (411)
Which IVACAFTOR Alternatives Have Lower Bronchiectasis Risk?
IVACAFTOR vs IVACAFTOR\LUMACAFTOR
IVACAFTOR vs IVACAFTOR\TEZACAFTOR
IVACAFTOR vs IVERMECTIN
IVACAFTOR vs IVOSIDENIB
IVACAFTOR vs IXABEPILONE