Does IVACAFTOR Cause Diarrhoea? 95 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 95 reports of Diarrhoea have been filed in association with IVACAFTOR (Kalydeco). This represents 1.4% of all adverse event reports for IVACAFTOR.
95
Reports of Diarrhoea with IVACAFTOR
1.4%
of all IVACAFTOR reports
5
Deaths
18
Hospitalizations
How Dangerous Is Diarrhoea From IVACAFTOR?
Of the 95 reports, 5 (5.3%) resulted in death, 18 (18.9%) required hospitalization, and 1 (1.1%) were considered life-threatening.
Is Diarrhoea Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IVACAFTOR. However, 95 reports have been filed with the FAERS database.
What Other Side Effects Does IVACAFTOR Cause?
Hospitalisation (1,209)
Infective pulmonary exacerbation of cystic fibrosis (550)
Infection (227)
Malaise (226)
Lower respiratory tract infection (224)
Pneumonia (215)
Death (203)
Cough (180)
Cystic fibrosis (167)
Headache (163)
What Other Drugs Cause Diarrhoea?
LENALIDOMIDE (27,576)
APREMILAST (23,752)
ADALIMUMAB (18,120)
METHOTREXATE (12,557)
TREPROSTINIL (11,335)
CAPECITABINE (9,277)
NINTEDANIB (9,103)
ETANERCEPT (8,856)
CABOZANTINIB S-MALATE (8,282)
RITUXIMAB (8,113)
Which IVACAFTOR Alternatives Have Lower Diarrhoea Risk?
IVACAFTOR vs IVACAFTOR\LUMACAFTOR
IVACAFTOR vs IVACAFTOR\TEZACAFTOR
IVACAFTOR vs IVERMECTIN
IVACAFTOR vs IVOSIDENIB
IVACAFTOR vs IXABEPILONE