Does IVACAFTOR Cause Respiratory failure? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Respiratory failure have been filed in association with IVACAFTOR (Kalydeco). This represents 0.5% of all adverse event reports for IVACAFTOR.
30
Reports of Respiratory failure with IVACAFTOR
0.5%
of all IVACAFTOR reports
17
Deaths
25
Hospitalizations
How Dangerous Is Respiratory failure From IVACAFTOR?
Of the 30 reports, 17 (56.7%) resulted in death, 25 (83.3%) required hospitalization, and 5 (16.7%) were considered life-threatening.
Is Respiratory failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for IVACAFTOR. However, 30 reports have been filed with the FAERS database.
What Other Side Effects Does IVACAFTOR Cause?
Hospitalisation (1,209)
Infective pulmonary exacerbation of cystic fibrosis (550)
Infection (227)
Malaise (226)
Lower respiratory tract infection (224)
Pneumonia (215)
Death (203)
Cough (180)
Cystic fibrosis (167)
Headache (163)
What Other Drugs Cause Respiratory failure?
PREDNISONE (2,299)
CYCLOPHOSPHAMIDE (2,096)
RITUXIMAB (1,838)
TACROLIMUS (1,758)
METHOTREXATE (1,685)
DEXAMETHASONE (1,603)
MYCOPHENOLATE MOFETIL (1,469)
METHYLPREDNISOLONE (1,442)
PREDNISOLONE (1,346)
VINCRISTINE (1,120)
Which IVACAFTOR Alternatives Have Lower Respiratory failure Risk?
IVACAFTOR vs IVACAFTOR\LUMACAFTOR
IVACAFTOR vs IVACAFTOR\TEZACAFTOR
IVACAFTOR vs IVERMECTIN
IVACAFTOR vs IVOSIDENIB
IVACAFTOR vs IXABEPILONE