KADCYLA: 150 Adverse Event Reports & Safety Profile
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150
Total FAERS Reports
37 (24.7%)
Deaths Reported
44
Hospitalizations
150
As Primary/Secondary Suspect
5
Life-Threatening
5
Disabilities
First Report: 2009 · Latest Report: 20140618
What Are the Most Common KADCYLA Side Effects?
#1 Most Reported
Disease progression
32 reports (21.3%)
#2 Most Reported
Febrile neutropenia
20 reports (13.3%)
#3 Most Reported
Death
18 reports (12.0%)
All KADCYLA Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Disease progression | 32 | 21.3% | 7 | 9 |
| Febrile neutropenia | 20 | 13.3% | 0 | 0 |
| Death | 18 | 12.0% | 18 | 4 |
| Nausea | 17 | 11.3% | 5 | 12 |
| Fatigue | 15 | 10.0% | 1 | 6 |
| Metastases to central nervous system | 9 | 6.0% | 3 | 4 |
| Pyrexia | 9 | 6.0% | 0 | 5 |
| Dyspnoea | 8 | 5.3% | 1 | 3 |
| Hypoaesthesia | 8 | 5.3% | 5 | 6 |
| Weight decreased | 8 | 5.3% | 0 | 2 |
| Diarrhoea | 7 | 4.7% | 0 | 2 |
| Headache | 7 | 4.7% | 1 | 3 |
| Hepatic enzyme increased | 7 | 4.7% | 4 | 4 |
| Paraesthesia | 7 | 4.7% | 1 | 2 |
| Constipation | 6 | 4.0% | 1 | 2 |
| Cough | 6 | 4.0% | 0 | 5 |
| Dizziness | 6 | 4.0% | 5 | 6 |
| Drug ineffective | 6 | 4.0% | 2 | 2 |
| Pneumonia | 6 | 4.0% | 2 | 2 |
| Vomiting | 6 | 4.0% | 0 | 3 |
Who Reports KADCYLA Side Effects? Age & Gender Data
Average age: 53.5 years. Most reports from: US. View detailed demographics →
Is KADCYLA Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2009 | 1 | 0 | 0 |
| 2010 | 1 | 0 | 0 |
| 2011 | 1 | 1 | 0 |
| 2012 | 4 | 0 | 1 |
| 2013 | 24 | 9 | 12 |
| 2014 | 40 | 9 | 16 |
What Is KADCYLA Used For?
| Indication | Reports |
|---|---|
| Breast cancer metastatic | 77 |
| Product used for unknown indication | 35 |
| Breast cancer | 19 |
| Her-2 positive breast cancer | 13 |
KADCYLA vs Alternatives: Which Is Safer?
KADCYLA vs KALBITOR
KADCYLA vs KALETRA
KADCYLA vs KANAMYCIN\KANAMYCIN A
KADCYLA vs KARDEGIC
KADCYLA vs KEPPRA
KADCYLA vs KETAMINE
KADCYLA vs KETOCONAZOLE
KADCYLA vs KETOPROFEN
KADCYLA vs KETOPROFEN LYSINE
KADCYLA vs KETOROLAC TROMETHAMINE
Official FDA Label for KADCYLA
Official prescribing information from the FDA-approved drug label.