LAROTRECTINIB for Osteosarcoma: Side Effects & Safety Data
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There are 5 adverse event reports in the FDA FAERS database where LAROTRECTINIB was used for Osteosarcoma.
Most Reported Side Effects for LAROTRECTINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 56 | 7.0% | 5 | 7 |
| Drug ineffective | 52 | 6.5% | 11 | 3 |
| Dizziness | 50 | 6.3% | 1 | 7 |
| Death | 48 | 6.0% | 48 | 2 |
| Pain | 42 | 5.3% | 4 | 9 |
| Neuropathy peripheral | 39 | 4.9% | 2 | 1 |
| Nausea | 32 | 4.0% | 1 | 5 |
| Off label use | 31 | 3.9% | 7 | 4 |
| Disease progression | 27 | 3.4% | 3 | 1 |
| Malignant neoplasm progression | 23 | 2.9% | 6 | 1 |
| Myalgia | 23 | 2.9% | 0 | 1 |
| Vomiting | 23 | 2.9% | 6 | 14 |
| Drug resistance | 19 | 2.4% | 3 | 1 |
| Anaemia | 18 | 2.3% | 3 | 7 |
| Diarrhoea | 18 | 2.3% | 3 | 9 |
Other Indications for LAROTRECTINIB
Thyroid cancer (43)
Neoplasm (31)
Neoplasm malignant (28)
Ntrk gene fusion cancer (26)
Ntrk gene fusion positive (25)
Sarcoma (25)
Lung neoplasm malignant (24)
Glioblastoma (21)
Congenital fibrosarcoma (18)
Pancreatic carcinoma (18)
Other Drugs Used for Osteosarcoma
METHOTREXATE (1,267)
DOXORUBICIN (1,135)
CISPLATIN (975)
IFOSFAMIDE (845)
ETOPOSIDE (531)
CARBOPLATIN (169)
CABOZANTINIB S-MALATE (116)
DOCETAXEL (99)
CYCLOPHOSPHAMIDE (92)
LENVATINIB (91)