Does LEFLUNOMIDE Cause Endocarditis? 44 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 44 reports of Endocarditis have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.1% of all adverse event reports for LEFLUNOMIDE.
44
Reports of Endocarditis with LEFLUNOMIDE
0.1%
of all LEFLUNOMIDE reports
14
Deaths
26
Hospitalizations
How Dangerous Is Endocarditis From LEFLUNOMIDE?
Of the 44 reports, 14 (31.8%) resulted in death, 26 (59.1%) required hospitalization, and 7 (15.9%) were considered life-threatening.
Is Endocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 44 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Endocarditis?
PREDNISONE (224)
PREDNISOLONE (176)
METHOTREXATE (170)
MYCOPHENOLATE MOFETIL (167)
DEXAMETHASONE (156)
TACROLIMUS (153)
RITUXIMAB (128)
CYCLOPHOSPHAMIDE (125)
VANCOMYCIN (110)
TOCILIZUMAB (104)
Which LEFLUNOMIDE Alternatives Have Lower Endocarditis Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM