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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

LETROZOLE\RIBOCICLIB: 621 Adverse Event Reports & Safety Profile

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621
Total FAERS Reports
78 (12.6%)
Deaths Reported
80
Hospitalizations
621
As Primary/Secondary Suspect
7
Life-Threatening
3
Disabilities

First Report: 20140806 · Latest Report: 20250207

What Are the Most Common LETROZOLE\RIBOCICLIB Side Effects?

#1 Most Reported
Fatigue
69 reports (11.1%)
#2 Most Reported
Death
66 reports (10.6%)
#3 Most Reported
Nausea
57 reports (9.2%)

All LETROZOLE\RIBOCICLIB Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Fatigue 69 11.1% 3 11
Death 66 10.6% 66 0
Nausea 57 9.2% 3 3
White blood cell count decreased 39 6.3% 2 6
Diarrhoea 35 5.6% 0 6
Rash 27 4.4% 1 0
Alopecia 25 4.0% 0 3
Neoplasm malignant 25 4.0% 1 3
Malaise 24 3.9% 0 1
Cough 22 3.5% 0 3
Disease progression 22 3.5% 1 1
Product dose omission issue 22 3.5% 0 5
Vomiting 22 3.5% 0 3
Headache 21 3.4% 0 2
Drug ineffective 20 3.2% 0 1
Pain 20 3.2% 0 5
Dyspnoea 19 3.1% 2 5
Dizziness 17 2.7% 1 3
Illness 17 2.7% 0 3
Constipation 16 2.6% 0 1

Who Reports LETROZOLE\RIBOCICLIB Side Effects? Age & Gender Data

Gender: 98.2% female, 1.8% male. Average age: 64.2 years. Most reports from: US. View detailed demographics →

Is LETROZOLE\RIBOCICLIB Getting Safer? Reports by Year

YearReportsDeathsHosp.
2014 1 0 1
2015 1 0 1
2016 1 0 1
2017 15 0 3
2018 56 4 11
2019 40 4 9
2020 33 5 7
2021 9 4 2
2022 21 6 2
2023 17 5 7
2024 8 1 1
2025 1 0 0

View full timeline →

What Is LETROZOLE\RIBOCICLIB Used For?

IndicationReports
Product used for unknown indication 327
Breast cancer 114
Breast cancer female 47
Breast cancer metastatic 44
Neoplasm malignant 16

LETROZOLE\RIBOCICLIB vs Alternatives: Which Is Safer?

LETROZOLE\RIBOCICLIB vs LEUCOVORIN LETROZOLE\RIBOCICLIB vs LEUCOVORIN\LEUCOVORIN LETROZOLE\RIBOCICLIB vs LEUPROLIDE LETROZOLE\RIBOCICLIB vs LEVALBUTEROL LETROZOLE\RIBOCICLIB vs LEVAMISOLE LETROZOLE\RIBOCICLIB vs LEVAQUIN LETROZOLE\RIBOCICLIB vs LEVEMIR LETROZOLE\RIBOCICLIB vs LEVETIRACETAM LETROZOLE\RIBOCICLIB vs LEVOBUNOLOL LETROZOLE\RIBOCICLIB vs LEVOBUPIVACAINE

Official FDA Label for LETROZOLE\RIBOCICLIB

Official prescribing information from the FDA-approved drug label.