LINZESS: 276 Adverse Event Reports & Safety Profile
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276
Total FAERS Reports
2 (0.7%)
Deaths Reported
15
Hospitalizations
276
As Primary/Secondary Suspect
1
Life-Threatening
2
Disabilities
First Report: 201212 · Latest Report: 20140620
What Are the Most Common LINZESS Side Effects?
#1 Most Reported
Diarrhoea
118 reports (42.8%)
#2 Most Reported
Drug ineffective
61 reports (22.1%)
#3 Most Reported
Abdominal pain
28 reports (10.1%)
All LINZESS Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 118 | 42.8% | 0 | 5 |
| Drug ineffective | 61 | 22.1% | 0 | 0 |
| Abdominal pain | 28 | 10.1% | 0 | 1 |
| Nausea | 22 | 8.0% | 0 | 2 |
| Abdominal distension | 19 | 6.9% | 0 | 2 |
| Intentional drug misuse | 19 | 6.9% | 0 | 0 |
| Flatulence | 16 | 5.8% | 0 | 0 |
| Abdominal pain upper | 15 | 5.4% | 0 | 1 |
| Off label use | 14 | 5.1% | 0 | 1 |
| Constipation | 11 | 4.0% | 0 | 1 |
| Asthenia | 8 | 2.9% | 0 | 1 |
| Dizziness | 7 | 2.5% | 0 | 1 |
| Faecal incontinence | 7 | 2.5% | 0 | 0 |
| Headache | 7 | 2.5% | 0 | 1 |
| Feeling abnormal | 6 | 2.2% | 0 | 0 |
| Palpitations | 5 | 1.8% | 0 | 1 |
Who Reports LINZESS Side Effects? Age & Gender Data
Average age: 64.0 years. Most reports from: US. View detailed demographics →
Is LINZESS Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2012 | 1 | 0 | 0 |
| 2013 | 94 | 0 | 4 |
| 2014 | 110 | 1 | 7 |
What Is LINZESS Used For?
| Indication | Reports |
|---|---|
| Constipation | 123 |
| Irritable bowel syndrome | 74 |
LINZESS vs Alternatives: Which Is Safer?
LINZESS vs LIORESAL
LINZESS vs LIORESAL INTRATHECAL /ML
LINZESS vs LIOTHYRONINE
LINZESS vs LIPEGFILGRASTIM
LINZESS vs LIPITOR
LINZESS vs LIRAGLUTIDE
LINZESS vs LISDEXAMFETAMINE
LINZESS vs LISDEXAMFETAMINE DIMESYLATE
LINZESS vs LISINOPRIL
LINZESS vs LISOCABTAGENE MARALEUCEL
Official FDA Label for LINZESS
Official prescribing information from the FDA-approved drug label.