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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

LISDEXAMFETAMINE: 851 Adverse Event Reports & Safety Profile

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851
Total FAERS Reports
153 (18.0%)
Deaths Reported
214
Hospitalizations
851
As Primary/Secondary Suspect
34
Life-Threatening
19
Disabilities

First Report: 2012 · Latest Report: 20250828

What Are the Most Common LISDEXAMFETAMINE Side Effects?

#1 Most Reported
Drug ineffective
164 reports (19.3%)
#2 Most Reported
Completed suicide
89 reports (10.5%)
#3 Most Reported
Anxiety
73 reports (8.6%)

All LISDEXAMFETAMINE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Drug ineffective 164 19.3% 0 9
Completed suicide 89 10.5% 89 25
Anxiety 73 8.6% 0 8
Toxicity to various agents 71 8.3% 50 39
Product substitution issue 65 7.6% 0 1
Insomnia 55 6.5% 0 5
Fatigue 53 6.2% 0 2
Headache 52 6.1% 0 9
Irritability 52 6.1% 0 10
Suicidal ideation 40 4.7% 1 8
Condition aggravated 37 4.4% 0 12
Aggression 36 4.2% 2 7
Nausea 35 4.1% 0 3
Speech disorder 35 4.1% 0 5
Feeling abnormal 33 3.9% 0 1
Cardio-respiratory arrest 32 3.8% 32 11
Sleep disorder 32 3.8% 0 0
Dyskinesia 31 3.6% 0 4
Crying 30 3.5% 0 1
Bruxism 29 3.4% 0 0

Who Reports LISDEXAMFETAMINE Side Effects? Age & Gender Data

Gender: 56.3% female, 43.7% male. Average age: 29.7 years. Most reports from: US. View detailed demographics →

Is LISDEXAMFETAMINE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2012 10 5 0
2013 4 3 0
2014 1 0 0
2015 9 5 0
2016 12 11 3
2017 18 8 6
2018 6 0 6
2020 7 6 1
2021 7 2 2
2022 14 10 5
2023 32 0 3
2024 42 1 8
2025 39 0 2

View full timeline →

What Is LISDEXAMFETAMINE Used For?

IndicationReports
Product used for unknown indication 389
Attention deficit hyperactivity disorder 215
Attention deficit/hyperactivity disorder 40
Binge eating 17
Disturbance in attention 13
Suicide attempt 8
Autism spectrum disorder 6
Depression 6
Decreased appetite 5

LISDEXAMFETAMINE vs Alternatives: Which Is Safer?

LISDEXAMFETAMINE vs LISDEXAMFETAMINE DIMESYLATE LISDEXAMFETAMINE vs LISINOPRIL LISDEXAMFETAMINE vs LISOCABTAGENE MARALEUCEL LISDEXAMFETAMINE vs LITHIUM LISDEXAMFETAMINE vs LIXISENATIDE LISDEXAMFETAMINE vs LOBAPLATIN LISDEXAMFETAMINE vs LOFEXIDINE LISDEXAMFETAMINE vs LOMITAPIDE LISDEXAMFETAMINE vs LOMUSTINE LISDEXAMFETAMINE vs LONAPEGSOMATROPIN-TCGD

Official FDA Label for LISDEXAMFETAMINE

Official prescribing information from the FDA-approved drug label.