LOPINAVIR\RITONAVIR for Covid-19 pneumonia: Side Effects & Safety Data
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There are 727 adverse event reports in the FDA FAERS database where LOPINAVIR\RITONAVIR was used for Covid-19 pneumonia.
Most Reported Side Effects for LOPINAVIR\RITONAVIR
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 2,010 | 24.2% | 370 | 798 |
| Foetal exposure during pregnancy | 932 | 11.2% | 147 | 101 |
| Drug interaction | 821 | 9.9% | 189 | 233 |
| Depression | 551 | 6.6% | 135 | 98 |
| Virologic failure | 428 | 5.2% | 20 | 33 |
| Exposure during pregnancy | 395 | 4.8% | 36 | 71 |
| Diarrhoea | 363 | 4.4% | 38 | 148 |
| Maternal exposure during pregnancy | 311 | 3.8% | 31 | 71 |
| Product use in unapproved indication | 282 | 3.4% | 76 | 135 |
| Nausea | 243 | 2.9% | 9 | 83 |
| Pathogen resistance | 234 | 2.8% | 16 | 25 |
| Lipodystrophy acquired | 230 | 2.8% | 0 | 16 |
| Acute kidney injury | 226 | 2.7% | 38 | 96 |
| Drug ineffective | 220 | 2.7% | 30 | 81 |
| Drug resistance | 220 | 2.7% | 19 | 44 |
Other Indications for LOPINAVIR\RITONAVIR
Hiv infection (3,387)
Covid-19 (1,549)
Product used for unknown indication (840)
Coronavirus infection (388)
Antiretroviral therapy (376)
Maternal exposure timing unspecified (278)
Acquired immunodeficiency syndrome (125)
Antiviral treatment (89)
Prophylaxis against hiv infection (86)
Hepatitis c (76)
Other Drugs Used for Covid-19 pneumonia
TOCILIZUMAB (1,583)
HYDROXYCHLOROQUINE (1,421)
REMDESIVIR (1,401)
DEXAMETHASONE (1,184)
AZITHROMYCIN ANHYDROUS (645)
CEFTRIAXONE (579)
METHYLPREDNISOLONE (450)
AZITHROMYCIN (408)
BARICITINIB (161)
PIPERACILLIN\TAZOBACTAM (159)