MABTHERA for Granulomatosis with polyangiitis: Side Effects & Safety Data
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There are 8 adverse event reports in the FDA FAERS database where MABTHERA was used for Granulomatosis with polyangiitis.
Most Reported Side Effects for MABTHERA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 71 | 11.3% | 71 | 3 |
| Pyrexia | 37 | 5.9% | 5 | 24 |
| Pain | 25 | 4.0% | 4 | 17 |
| Progressive multifocal leukoencephalopathy | 25 | 4.0% | 6 | 10 |
| Dyspnoea | 23 | 3.7% | 4 | 14 |
| Vomiting | 23 | 3.7% | 1 | 22 |
| Arthralgia | 22 | 3.5% | 0 | 17 |
| Drug ineffective | 22 | 3.5% | 2 | 12 |
| Infection | 20 | 3.2% | 1 | 15 |
| Malaise | 20 | 3.2% | 0 | 12 |
| Diarrhoea | 19 | 3.0% | 3 | 14 |
| Headache | 18 | 2.9% | 2 | 15 |
| Neutropenia | 18 | 2.9% | 2 | 9 |
| Pain in extremity | 18 | 2.9% | 0 | 11 |
| Pneumonia | 18 | 2.9% | 5 | 11 |
Other Indications for MABTHERA
Rheumatoid arthritis (169)
Non-hodgkin's lymphoma (100)
Product used for unknown indication (66)
B-cell lymphoma (52)
Chronic lymphocytic leukaemia (44)
Diffuse large b-cell lymphoma (39)
Lymphoma (27)
Mantle cell lymphoma (16)
Systemic lupus erythematosus (11)
Non-hodgkin's lymphoma unspecified histology aggressive (9)
Other Drugs Used for Granulomatosis with polyangiitis
RITUXIMAB (3,222)
AVACOPAN (931)
RITUXIMAB-PVVR (745)
METHOTREXATE (456)
CYCLOPHOSPHAMIDE (438)
PREDNISONE (410)
PREDNISOLONE (299)
AZATHIOPRINE (265)
MYCOPHENOLATE MOFETIL (237)
METHYLPREDNISOLONE (210)