MELPERONE: 589 Adverse Event Reports & Safety Profile
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589
Total FAERS Reports
131 (22.2%)
Deaths Reported
356
Hospitalizations
589
As Primary/Secondary Suspect
93
Life-Threatening
9
Disabilities
First Report: 19970630 · Latest Report: 20250621
What Are the Most Common MELPERONE Side Effects?
#1 Most Reported
Fall
105 reports (17.8%)
#2 Most Reported
Diarrhoea
71 reports (12.1%)
#3 Most Reported
Restlessness
62 reports (10.5%)
All MELPERONE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Fall | 105 | 17.8% | 2 | 82 |
| Diarrhoea | 71 | 12.1% | 38 | 62 |
| Restlessness | 62 | 10.5% | 33 | 49 |
| Nausea | 53 | 9.0% | 36 | 47 |
| Vomiting | 52 | 8.8% | 0 | 36 |
| Toxic epidermal necrolysis | 50 | 8.5% | 50 | 41 |
| Condition aggravated | 49 | 8.3% | 29 | 38 |
| Multiple organ dysfunction syndrome | 49 | 8.3% | 49 | 37 |
| Respiratory disorder | 47 | 8.0% | 44 | 36 |
| Somnolence | 46 | 7.8% | 0 | 37 |
| Blister | 44 | 7.5% | 44 | 30 |
| Hypotension | 43 | 7.3% | 0 | 38 |
| Syncope | 39 | 6.6% | 0 | 32 |
| Intentional overdose | 37 | 6.3% | 0 | 23 |
| Tachycardia | 37 | 6.3% | 0 | 35 |
| Cholecystitis | 36 | 6.1% | 36 | 35 |
| Electrolyte imbalance | 36 | 6.1% | 36 | 35 |
| Hyperthyroidism | 36 | 6.1% | 36 | 36 |
| Dizziness | 35 | 5.9% | 0 | 18 |
| Delirium | 34 | 5.8% | 0 | 17 |
Who Reports MELPERONE Side Effects? Age & Gender Data
Gender: 64.3% female, 35.7% male. Average age: 65.6 years. Most reports from: DE. View detailed demographics →
Is MELPERONE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2001 | 42 | 42 | 36 |
| 2002 | 3 | 0 | 3 |
| 2004 | 19 | 15 | 4 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 0 | 2 |
| 2009 | 7 | 1 | 7 |
| 2010 | 13 | 0 | 3 |
| 2011 | 17 | 6 | 15 |
| 2012 | 11 | 0 | 8 |
| 2013 | 8 | 1 | 1 |
| 2014 | 17 | 0 | 7 |
| 2015 | 42 | 8 | 25 |
| 2016 | 33 | 7 | 14 |
| 2017 | 15 | 4 | 9 |
| 2018 | 16 | 0 | 10 |
| 2019 | 17 | 0 | 16 |
| 2020 | 8 | 0 | 3 |
| 2021 | 6 | 0 | 2 |
| 2022 | 2 | 0 | 1 |
| 2023 | 4 | 0 | 3 |
| 2024 | 9 | 0 | 3 |
| 2025 | 3 | 0 | 0 |
What Is MELPERONE Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 365 |
| Restlessness | 47 |
| Sleep disorder | 20 |
| Depression | 13 |
| Antipsychotic therapy | 7 |
| Ill-defined disorder | 7 |
| Major depression | 7 |
| Intellectual disability | 6 |
| Schizophrenia | 6 |
MELPERONE vs Alternatives: Which Is Safer?
MELPERONE vs MELPHALAN
MELPERONE vs MEMANTINE
MELPERONE vs MENINGOCOCCAL GROUP B VACCINE
MELPERONE vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPERONE vs MENOTROPINS
MELPERONE vs MENTHOL
MELPERONE vs MENTHOL\METHYL SALICYLATE
MELPERONE vs MENTHOL\ZINC
MELPERONE vs MEPERIDINE
MELPERONE vs MEPIVACAINE
Official FDA Label for MELPERONE
Official prescribing information from the FDA-approved drug label.