Does MEPOLIZUMAB Cause Aphonia? 139 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 139 reports of Aphonia have been filed in association with MEPOLIZUMAB (Nucala). This represents 0.3% of all adverse event reports for MEPOLIZUMAB.
139
Reports of Aphonia with MEPOLIZUMAB
0.3%
of all MEPOLIZUMAB reports
2
Deaths
63
Hospitalizations
How Dangerous Is Aphonia From MEPOLIZUMAB?
Of the 139 reports, 2 (1.4%) resulted in death, 63 (45.3%) required hospitalization, and 2 (1.4%) were considered life-threatening.
Is Aphonia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MEPOLIZUMAB. However, 139 reports have been filed with the FAERS database.
What Other Side Effects Does MEPOLIZUMAB Cause?
Asthma (11,033)
Dyspnoea (9,192)
Wheezing (6,093)
Product dose omission issue (5,873)
Cough (4,577)
Pneumonia (4,107)
Therapeutic product effect incomplete (4,106)
Drug ineffective (3,880)
Loss of personal independence in daily activities (3,566)
Fatigue (2,656)
What Other Drugs Cause Aphonia?
AMIKACIN (465)
ADALIMUMAB (397)
OMALIZUMAB (338)
FLUTICASONE\SALMETEROL (300)
ETANERCEPT (278)
BUDESONIDE\FORMOTEROL (274)
DUPILUMAB (259)
TOFACITINIB (248)
TIOTROPIUM (227)
LENALIDOMIDE (207)
Which MEPOLIZUMAB Alternatives Have Lower Aphonia Risk?
MEPOLIZUMAB vs MEPROBAMATE
MEPOLIZUMAB vs MERCAPTOPURINE
MEPOLIZUMAB vs MEROPENEM
MEPOLIZUMAB vs MEROPENEM ANHYDROUS
MEPOLIZUMAB vs MESALAMINE