Does METFORMIN Cause Anion gap increased? 172 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 172 reports of Anion gap increased have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.2% of all adverse event reports for METFORMIN.
172
Reports of Anion gap increased with METFORMIN
0.2%
of all METFORMIN reports
27
Deaths
138
Hospitalizations
How Dangerous Is Anion gap increased From METFORMIN?
Of the 172 reports, 27 (15.7%) resulted in death, 138 (80.2%) required hospitalization, and 29 (16.9%) were considered life-threatening.
Is Anion gap increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 172 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Anion gap increased?
ACETAMINOPHEN (84)
CLOZAPINE (63)
QUETIAPINE (51)
EMPAGLIFLOZIN (50)
CLONAZEPAM (47)
SOMATROPIN (35)
ALPRAZOLAM (30)
LORAZEPAM (29)
ZOPICLONE (28)
ATORVASTATIN (27)
Which METFORMIN Alternatives Have Lower Anion gap increased Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN