Does METFORMIN Cause Cholelithiasis? 288 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 288 reports of Cholelithiasis have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.3% of all adverse event reports for METFORMIN.
288
Reports of Cholelithiasis with METFORMIN
0.3%
of all METFORMIN reports
40
Deaths
173
Hospitalizations
How Dangerous Is Cholelithiasis From METFORMIN?
Of the 288 reports, 40 (13.9%) resulted in death, 173 (60.1%) required hospitalization, and 44 (15.3%) were considered life-threatening.
Is Cholelithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 288 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Cholelithiasis?
ADALIMUMAB (1,238)
OCTREOTIDE (641)
SEMAGLUTIDE (571)
METHOTREXATE (466)
TIRZEPATIDE (386)
PREDNISONE (346)
ETANERCEPT (345)
ACETAMINOPHEN (313)
LENALIDOMIDE (308)
CEFTRIAXONE (306)
Which METFORMIN Alternatives Have Lower Cholelithiasis Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN