Does METFORMIN Cause Hyperthyroidism? 134 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 134 reports of Hyperthyroidism have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.2% of all adverse event reports for METFORMIN.
134
Reports of Hyperthyroidism with METFORMIN
0.2%
of all METFORMIN reports
38
Deaths
60
Hospitalizations
How Dangerous Is Hyperthyroidism From METFORMIN?
Of the 134 reports, 38 (28.4%) resulted in death, 60 (44.8%) required hospitalization, and 36 (26.9%) were considered life-threatening.
Is Hyperthyroidism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 134 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Hyperthyroidism?
LEVOTHYROXINE (1,681)
AMIODARONE (1,410)
NIVOLUMAB (934)
PEMBROLIZUMAB (780)
IPILIMUMAB (525)
CARBOPLATIN (432)
ATEZOLIZUMAB (416)
PACLITAXEL (261)
ALEMTUZUMAB (236)
LENVATINIB (231)
Which METFORMIN Alternatives Have Lower Hyperthyroidism Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN