Does METFORMIN Cause Hypovolaemia? 281 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 281 reports of Hypovolaemia have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.3% of all adverse event reports for METFORMIN.
281
Reports of Hypovolaemia with METFORMIN
0.3%
of all METFORMIN reports
14
Deaths
259
Hospitalizations
How Dangerous Is Hypovolaemia From METFORMIN?
Of the 281 reports, 14 (5.0%) resulted in death, 259 (92.2%) required hospitalization, and 58 (20.6%) were considered life-threatening.
Is Hypovolaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 281 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Hypovolaemia?
FUROSEMIDE (346)
EMPAGLIFLOZIN (150)
SPIRONOLACTONE (123)
DEXAMETHASONE (117)
HYDROCHLOROTHIAZIDE (94)
PREDNISONE (91)
LISINOPRIL (86)
METOPROLOL (84)
ACETAMINOPHEN (77)
SACUBITRIL\VALSARTAN (73)
Which METFORMIN Alternatives Have Lower Hypovolaemia Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN