METFORMIN\SAXAGLIPTIN: 1,093 Adverse Event Reports & Safety Profile
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1,093
Total FAERS Reports
117 (10.7%)
Deaths Reported
336
Hospitalizations
1,093
As Primary/Secondary Suspect
29
Life-Threatening
27
Disabilities
Active Ingredient: METFORMIN HYDROCHLORIDE\SAXAGLIPTIN HYDROCHLORIDE ·
First Report: 1980 · Latest Report: 20250618
What Are the Most Common METFORMIN\SAXAGLIPTIN Side Effects?
#1 Most Reported
Cardiac failure congestive
296 reports (27.1%)
#2 Most Reported
Cardiac failure
256 reports (23.4%)
#3 Most Reported
Cardiovascular disorder
154 reports (14.1%)
All METFORMIN\SAXAGLIPTIN Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Cardiac failure congestive | 296 | 27.1% | 48 | 117 |
| Cardiac failure | 256 | 23.4% | 38 | 98 |
| Cardiovascular disorder | 154 | 14.1% | 10 | 52 |
| Blood glucose increased | 84 | 7.7% | 1 | 11 |
| Diarrhoea | 62 | 5.7% | 5 | 7 |
| Death | 53 | 4.9% | 53 | 4 |
| Off label use | 43 | 3.9% | 2 | 10 |
| Nausea | 42 | 3.8% | 0 | 12 |
| Coronary artery disease | 41 | 3.8% | 8 | 24 |
| Myocardial infarction | 41 | 3.8% | 2 | 32 |
| Vomiting | 40 | 3.7% | 0 | 12 |
| Drug dose omission | 39 | 3.6% | 0 | 2 |
| Acute left ventricular failure | 38 | 3.5% | 3 | 31 |
| Drug ineffective | 37 | 3.4% | 0 | 5 |
| Pancreatitis | 33 | 3.0% | 2 | 18 |
| Glycosylated haemoglobin increased | 31 | 2.8% | 0 | 5 |
| Intentional product misuse | 30 | 2.7% | 0 | 4 |
| Hyperglycaemia | 29 | 2.7% | 0 | 10 |
| Lactic acidosis | 29 | 2.7% | 13 | 18 |
| Medication residue present | 28 | 2.6% | 0 | 1 |
Who Reports METFORMIN\SAXAGLIPTIN Side Effects? Age & Gender Data
Gender: 50.0% female, 50.0% male. Average age: 61.4 years. Most reports from: US. View detailed demographics →
Is METFORMIN\SAXAGLIPTIN Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 0 |
| 2007 | 2 | 0 | 1 |
| 2008 | 4 | 1 | 2 |
| 2009 | 2 | 0 | 1 |
| 2010 | 8 | 0 | 3 |
| 2011 | 14 | 0 | 8 |
| 2012 | 29 | 3 | 18 |
| 2013 | 32 | 6 | 21 |
| 2014 | 121 | 8 | 45 |
| 2015 | 114 | 8 | 59 |
| 2016 | 76 | 5 | 38 |
| 2017 | 61 | 5 | 28 |
| 2018 | 32 | 3 | 13 |
| 2019 | 17 | 6 | 1 |
| 2020 | 7 | 2 | 2 |
| 2021 | 20 | 5 | 4 |
| 2022 | 11 | 0 | 4 |
| 2023 | 12 | 2 | 3 |
| 2024 | 30 | 3 | 23 |
| 2025 | 6 | 0 | 3 |
What Is METFORMIN\SAXAGLIPTIN Used For?
| Indication | Reports |
|---|---|
| Type 2 diabetes mellitus | 467 |
| Diabetes mellitus | 194 |
| Product used for unknown indication | 47 |
| Blood glucose abnormal | 9 |
| Blood glucose increased | 6 |
| Glucose tolerance impaired | 5 |
METFORMIN\SAXAGLIPTIN vs Alternatives: Which Is Safer?
METFORMIN\SAXAGLIPTIN vs METFORMIN\SITAGLIPTIN
METFORMIN\SAXAGLIPTIN vs METFORMIN\VILDAGLIPTIN
METFORMIN\SAXAGLIPTIN vs METHADONE
METFORMIN\SAXAGLIPTIN vs METHAMPHETAMINE
METFORMIN\SAXAGLIPTIN vs METHENAMINE HIPPURATE
METFORMIN\SAXAGLIPTIN vs METHIMAZOLE
METFORMIN\SAXAGLIPTIN vs METHOCARBAMOL
METFORMIN\SAXAGLIPTIN vs METHOHEXITAL
METFORMIN\SAXAGLIPTIN vs METHOTREXATE
METFORMIN\SAXAGLIPTIN vs METHOXSALEN
Official FDA Label for METFORMIN\SAXAGLIPTIN
Official prescribing information from the FDA-approved drug label.