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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

METHACHOLINE vs VARENICLINE: Which Drug Is Safer?

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METHACHOLINE vs VARENICLINE: Safety Overview

Metric METHACHOLINE VARENICLINE
Total FAERS Reports 36 20,408
Deaths Reported 6 458
Death Rate 16.7% 2.2%
Hospitalizations 7 1,754
Average Patient Age 44.5 yrs 55.3 yrs
% Female Patients 87.0% 63.9%
FDA Approval Date Aug 29, 2016 Apr 8, 2025
Manufacturer Methapharm Inc. Marlex Pharmaceuticals, Inc.
Route RESPIRATORY (INHALATION) ORAL
Marketing Status Prescription Prescription