Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

METHADONE vs METHOTREXATE: Which Drug Is Safer?

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now

METHADONE vs METHOTREXATE: Safety Overview

Metric METHADONE METHOTREXATE
Total FAERS Reports 26,279 253,987
Deaths Reported 10,719 21,265
Death Rate 40.8% 8.4%
Hospitalizations 5,514 68,793
Average Patient Age 42.4 yrs 49.6 yrs
% Female Patients 42.6% 74.7%
FDA Approval Date Approved Prior to Jan 1, 1982 Approved Prior to Jan 1, 1982
Manufacturer Hikma Pharmaceuticals USA Inc. Accord Healthcare Inc.
Route ORAL ORAL
Marketing Status Discontinued Discontinued