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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

METHOTREXATE vs PEMETREXED: Which Drug Is Safer?

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METHOTREXATE vs PEMETREXED: Safety Overview

Metric METHOTREXATE PEMETREXED
Total FAERS Reports 253,987 23,543
Deaths Reported 21,265 3,876
Death Rate 8.4% 16.5%
Hospitalizations 68,793 10,697
Average Patient Age 49.6 yrs 63.6 yrs
% Female Patients 74.7% 41.0%
FDA Approval Date Approved Prior to Jan 1, 1982 Aug 18, 2022
Manufacturer Accord Healthcare Inc. BluePoint Laboratories
Route ORAL INTRAVENOUS
Marketing Status Discontinued Prescription