METRONIDAZOLE\SPIRAMYCIN: 78 Adverse Event Reports & Safety Profile
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78
Total FAERS Reports
2 (2.6%)
Deaths Reported
48
Hospitalizations
78
As Primary/Secondary Suspect
First Report: 20110226 · Latest Report: 20241008
What Are the Most Common METRONIDAZOLE\SPIRAMYCIN Side Effects?
#1 Most Reported
Hepatocellular injury
15 reports (19.2%)
#2 Most Reported
Rash maculo-papular
9 reports (11.5%)
#3 Most Reported
Pyrexia
9 reports (11.5%)
All METRONIDAZOLE\SPIRAMYCIN Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Hepatocellular injury | 15 | 19.2% | 0 | 10 |
| Pyrexia | 9 | 11.5% | 0 | 8 |
| Rash maculo-papular | 9 | 11.5% | 0 | 8 |
| Pruritus | 8 | 10.3% | 0 | 7 |
| Systemic lupus erythematosus | 7 | 9.0% | 0 | 7 |
| Vomiting | 7 | 9.0% | 0 | 2 |
| Abdominal pain | 6 | 7.7% | 0 | 1 |
| Conjunctival hyperaemia | 6 | 7.7% | 0 | 6 |
| Eyelid oedema | 6 | 7.7% | 0 | 6 |
| Action tremor | 5 | 6.4% | 0 | 0 |
| Agranulocytosis | 5 | 6.4% | 0 | 4 |
| Amyotrophy | 5 | 6.4% | 0 | 0 |
| Angioedema | 5 | 6.4% | 0 | 4 |
| Asthenia | 5 | 6.4% | 0 | 0 |
| Diarrhoea | 5 | 6.4% | 0 | 1 |
| Generalised oedema | 5 | 6.4% | 0 | 0 |
| Insomnia | 5 | 6.4% | 0 | 0 |
| Skin disorder | 5 | 6.4% | 0 | 0 |
Who Reports METRONIDAZOLE\SPIRAMYCIN Side Effects? Age & Gender Data
Gender: 64.6% female, 35.4% male. Average age: 50.5 years. Most reports from: FR. View detailed demographics →
Is METRONIDAZOLE\SPIRAMYCIN Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 6 | 0 | 4 |
| 2015 | 2 | 2 | 0 |
| 2016 | 1 | 0 | 0 |
| 2017 | 7 | 0 | 7 |
| 2018 | 9 | 0 | 3 |
| 2019 | 20 | 0 | 16 |
| 2020 | 11 | 0 | 6 |
| 2021 | 2 | 0 | 0 |
| 2024 | 6 | 0 | 6 |
What Is METRONIDAZOLE\SPIRAMYCIN Used For?
| Indication | Reports |
|---|---|
| Tooth infection | 14 |
| Product used for unknown indication | 13 |
| Tooth abscess | 8 |
| Dental operation | 5 |
| Tooth extraction | 5 |
Official FDA Label for METRONIDAZOLE\SPIRAMYCIN
Official prescribing information from the FDA-approved drug label.