METYRAPONE for Hyperadrenocorticism: Side Effects & Safety Data
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There are 27 adverse event reports in the FDA FAERS database where METYRAPONE was used for Hyperadrenocorticism.
Most Reported Side Effects for METYRAPONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 277 | 50.3% | 9 | 20 |
| Nausea | 53 | 9.6% | 3 | 13 |
| Drug ineffective | 39 | 7.1% | 4 | 18 |
| Pneumocystis jirovecii pneumonia | 31 | 5.6% | 8 | 25 |
| Fatigue | 30 | 5.4% | 5 | 3 |
| Vomiting | 27 | 4.9% | 2 | 10 |
| Dizziness | 26 | 4.7% | 0 | 2 |
| Adrenal insufficiency | 23 | 4.2% | 2 | 11 |
| Anaemia | 23 | 4.2% | 2 | 7 |
| Exposure during pregnancy | 22 | 4.0% | 0 | 5 |
| Asthenia | 20 | 3.6% | 2 | 3 |
| Diarrhoea | 20 | 3.6% | 0 | 6 |
| Premature baby | 19 | 3.5% | 0 | 7 |
| Maternal exposure during pregnancy | 18 | 3.3% | 1 | 5 |
| Foetal exposure during pregnancy | 16 | 2.9% | 0 | 5 |
Other Indications for METYRAPONE
Cushing's syndrome (177)
Pituitary-dependent cushing's syndrome (88)
Product used for unknown indication (37)
Adrenal gland cancer (33)
Ectopic acth syndrome (32)
Adrenocortical carcinoma (11)
Cortisol increased (11)
Diagnostic procedure (8)
Exposure during pregnancy (8)
Hypercorticoidism (6)
Other Drugs Used for Hyperadrenocorticism
KETOCONAZOLE (54)
MIFEPRISTONE (45)
OSILODROSTAT (23)
ETOMIDATE (10)
TRIPTORELIN (9)
HYDROCORTISONE (7)
BEVACIZUMAB (6)
CISPLATIN (6)
DOXORUBICIN (6)
ETOPOSIDE (6)