MIRENA: 3,769 Adverse Event Reports & Safety Profile
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3,769
Total FAERS Reports
8 (0.2%)
Deaths Reported
597
Hospitalizations
3,769
As Primary/Secondary Suspect
80
Life-Threatening
41
Disabilities
First Report: 2000 · Latest Report: 20140624
What Are the Most Common MIRENA Side Effects?
#1 Most Reported
Device expulsion
1,300 reports (34.5%)
#2 Most Reported
Injury
788 reports (20.9%)
#3 Most Reported
Pain
685 reports (18.2%)
All MIRENA Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Device expulsion | 1,300 | 34.5% | 0 | 10 |
| Injury | 788 | 20.9% | 0 | 467 |
| Pain | 685 | 18.2% | 0 | 296 |
| Device dislocation | 677 | 18.0% | 0 | 182 |
| Uterine perforation | 644 | 17.1% | 0 | 395 |
| Emotional distress | 577 | 15.3% | 0 | 363 |
| Genital haemorrhage | 410 | 10.9% | 0 | 75 |
| Abdominal pain lower | 342 | 9.1% | 0 | 89 |
| Device difficult to use | 307 | 8.2% | 0 | 77 |
| Device issue | 292 | 7.8% | 0 | 205 |
| Abdominal pain | 286 | 7.6% | 0 | 119 |
| Anxiety | 281 | 7.5% | 0 | 209 |
| Depression | 239 | 6.3% | 0 | 166 |
| Procedural pain | 217 | 5.8% | 0 | 49 |
| Drug ineffective | 203 | 5.4% | 0 | 82 |
| Pelvic pain | 186 | 4.9% | 0 | 81 |
| Pregnancy with contraceptive device | 162 | 4.3% | 0 | 58 |
| Embedded device | 159 | 4.2% | 0 | 44 |
| Device misuse | 155 | 4.1% | 0 | 47 |
| Menorrhagia | 145 | 3.9% | 0 | 61 |
Who Reports MIRENA Side Effects? Age & Gender Data
Average age: 31.0 years. Most reports from: US. View detailed demographics →
Is MIRENA Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 2 | 0 | 0 |
| 2002 | 2 | 0 | 2 |
| 2003 | 4 | 0 | 4 |
| 2004 | 5 | 0 | 2 |
| 2005 | 10 | 0 | 3 |
| 2006 | 18 | 0 | 13 |
| 2007 | 40 | 0 | 25 |
| 2008 | 57 | 0 | 34 |
| 2009 | 63 | 1 | 33 |
| 2010 | 106 | 1 | 69 |
| 2011 | 155 | 1 | 101 |
| 2012 | 185 | 0 | 100 |
| 2013 | 553 | 0 | 74 |
| 2014 | 1,220 | 0 | 26 |
What Is MIRENA Used For?
| Indication | Reports |
|---|---|
| Contraception | 2,813 |
| Menorrhagia | 383 |
| Endometriosis | 12 |
| Menstrual cycle management | 12 |
| Product used for unknown indication | 12 |
| Dysmenorrhoea | 10 |
| Adenomyosis | 6 |
| Genital haemorrhage | 6 |
| Uterine leiomyoma | 6 |
| Menstruation irregular | 5 |
MIRENA vs Alternatives: Which Is Safer?
MIRENA vs MIRIKIZUMAB-MRKZ
MIRENA vs MIRTAZAPINE
MIRENA vs MIRVETUXIMAB SORAVTANSINE-GYNX
MIRENA vs MISOPROSTOL
MIRENA vs MITAPIVAT
MIRENA vs MITOMYCIN
MIRENA vs MITOTANE
MIRENA vs MITOXANTRONE
MIRENA vs MITRAGYNINE\HERBALS
MIRENA vs MIZORIBINE
Official FDA Label for MIRENA
Official prescribing information from the FDA-approved drug label.