NAFRONYL: 116 Adverse Event Reports & Safety Profile
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116
Total FAERS Reports
24 (20.7%)
Deaths Reported
63
Hospitalizations
116
As Primary/Secondary Suspect
10
Life-Threatening
13
Disabilities
First Report: 20011231 · Latest Report: 20210408
What Are the Most Common NAFRONYL Side Effects?
#1 Most Reported
Acute kidney injury
22 reports (19.0%)
#2 Most Reported
Toxicity to various agents
19 reports (16.4%)
#3 Most Reported
Hepatic cytolysis
19 reports (16.4%)
All NAFRONYL Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Acute kidney injury | 22 | 19.0% | 3 | 20 |
| Hepatic cytolysis | 19 | 16.4% | 19 | 13 |
| Toxicity to various agents | 19 | 16.4% | 19 | 13 |
| Acute pulmonary oedema | 18 | 15.5% | 18 | 12 |
| Cardiac disorder | 17 | 14.7% | 17 | 11 |
| Lactic acidosis | 14 | 12.1% | 2 | 9 |
| Synovitis | 14 | 12.1% | 14 | 13 |
| Cerebral haemorrhage | 13 | 11.2% | 0 | 0 |
| Anaemia | 12 | 10.3% | 0 | 0 |
| Coronary artery stenosis | 12 | 10.3% | 12 | 11 |
| Encephalopathy | 12 | 10.3% | 12 | 7 |
| Renal cell carcinoma | 12 | 10.3% | 0 | 0 |
| Respiratory depression | 12 | 10.3% | 12 | 7 |
| Drug abuse | 11 | 9.5% | 11 | 10 |
| Hyperkalaemia | 11 | 9.5% | 1 | 11 |
| Intentional self-injury | 11 | 9.5% | 11 | 10 |
| Anuria | 9 | 7.8% | 0 | 9 |
| Cardio-respiratory arrest | 9 | 7.8% | 9 | 7 |
| Hypocalcaemia | 9 | 7.8% | 0 | 9 |
| Hypomagnesaemia | 9 | 7.8% | 0 | 9 |
Who Reports NAFRONYL Side Effects? Age & Gender Data
Gender: 24.1% female, 75.9% male. Average age: 65.8 years. Most reports from: FR. View detailed demographics →
Is NAFRONYL Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2001 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 1 | 1 |
| 2013 | 4 | 0 | 1 |
| 2014 | 12 | 0 | 0 |
| 2015 | 2 | 2 | 2 |
| 2016 | 25 | 21 | 17 |
| 2017 | 9 | 0 | 9 |
| 2018 | 23 | 0 | 23 |
| 2019 | 7 | 0 | 5 |
| 2020 | 14 | 0 | 0 |
| 2021 | 1 | 0 | 0 |
What Is NAFRONYL Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 63 |
| Intermittent claudication | 13 |
| Thromboangiitis obliterans | 12 |
| Peripheral vascular disorder | 8 |
| Peripheral arterial occlusive disease | 7 |
NAFRONYL vs Alternatives: Which Is Safer?
NAFRONYL vs NAFTIFINE
NAFRONYL vs NAGLAZYME
NAFRONYL vs NALBUPHINE
NAFRONYL vs NALDEMEDINE
NAFRONYL vs NALMEFENE
NAFRONYL vs NALOXEGOL OXALATE
NAFRONYL vs NALOXONE
NAFRONYL vs NALOXONE\OXYCODONE
NAFRONYL vs NALOXONE\TILIDINE
NAFRONYL vs NALTREXONE
Official FDA Label for NAFRONYL
Official prescribing information from the FDA-approved drug label.