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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

NETUPITANT\PALONOSETRON: 420 Adverse Event Reports & Safety Profile

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420
Total FAERS Reports
81 (19.3%)
Deaths Reported
142
Hospitalizations
420
As Primary/Secondary Suspect
21
Life-Threatening
10
Disabilities

Active Ingredient: NETUPITANT\PALONOSETRON HYDROCHLORIDE ·

First Report: 20141102 · Latest Report: 20250902

What Are the Most Common NETUPITANT\PALONOSETRON Side Effects?

#1 Most Reported
Nausea
58 reports (13.8%)
#2 Most Reported
Death
55 reports (13.1%)
#3 Most Reported
Vomiting
45 reports (10.7%)

All NETUPITANT\PALONOSETRON Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Nausea 58 13.8% 2 22
Death 55 13.1% 51 1
Vomiting 45 10.7% 0 26
Drug interaction 25 6.0% 1 14
Dyspnoea 21 5.0% 1 6
Hypotension 21 5.0% 0 14
Off label use 21 5.0% 2 11
Constipation 19 4.5% 0 10
Rheumatoid nodule 19 4.5% 0 0
Tachycardia 19 4.5% 1 10
Disease progression 17 4.1% 4 2
Fatigue 17 4.1% 0 2
Drug ineffective 16 3.8% 1 5
Diarrhoea 14 3.3% 0 12
Neutropenia 14 3.3% 2 9
Serotonin syndrome 14 3.3% 0 1
Thrombocytopenia 13 3.1% 10 2
Cerebrovascular accident 12 2.9% 10 0
Malaise 12 2.9% 0 6
Deafness neurosensory 11 2.6% 0 0

Who Reports NETUPITANT\PALONOSETRON Side Effects? Age & Gender Data

Gender: 66.2% female, 33.8% male. Average age: 58.0 years. Most reports from: US. View detailed demographics →

Is NETUPITANT\PALONOSETRON Getting Safer? Reports by Year

YearReportsDeathsHosp.
2014 1 0 1
2015 8 0 3
2016 10 0 8
2017 25 4 19
2018 37 8 7
2019 55 11 30
2020 53 12 8
2021 47 4 23
2022 11 4 4
2023 32 10 6
2024 17 0 11
2025 9 0 3

View full timeline →

What Is NETUPITANT\PALONOSETRON Used For?

IndicationReports
Prophylaxis of nausea and vomiting 180
Product used for unknown indication 64
Nausea 33
Vomiting 16
Lung neoplasm malignant 13
Colon neoplasm 10
Premedication 9
Squamous cell carcinoma 7
Pancreatic carcinoma 6
Colon cancer 5

NETUPITANT\PALONOSETRON vs Alternatives: Which Is Safer?

NETUPITANT\PALONOSETRON vs NEULASTA NETUPITANT\PALONOSETRON vs NEUPOGEN NETUPITANT\PALONOSETRON vs NEUPRO NETUPITANT\PALONOSETRON vs NEURONTIN NETUPITANT\PALONOSETRON vs NEVIRAPINE NETUPITANT\PALONOSETRON vs NEXAVAR NETUPITANT\PALONOSETRON vs NEXIUM NETUPITANT\PALONOSETRON vs NEXPLANON NETUPITANT\PALONOSETRON vs NIACIN NETUPITANT\PALONOSETRON vs NIACINAMIDE

Official FDA Label for NETUPITANT\PALONOSETRON

Official prescribing information from the FDA-approved drug label.