Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

NIRMATRELVIR\RITONAVIR: 52,157 Adverse Event Reports & Safety Profile

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now
52,157
Total FAERS Reports
484 (0.9%)
Deaths Reported
2,738
Hospitalizations
52,157
As Primary/Secondary Suspect
486
Life-Threatening
511
Disabilities

First Report: 10220830 · Latest Report: 20250929

What Are the Most Common NIRMATRELVIR\RITONAVIR Side Effects?

#1 Most Reported
Covid-19
22,066 reports (42.3%)
#2 Most Reported
Disease recurrence
20,040 reports (38.4%)
#3 Most Reported
Dysgeusia
7,381 reports (14.2%)

All NIRMATRELVIR\RITONAVIR Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Covid-19 22,066 42.3% 53 412
Disease recurrence 20,040 38.4% 17 273
Dysgeusia 7,381 14.2% 3 192
Diarrhoea 3,999 7.7% 11 305
Nausea 2,618 5.0% 11 235
Headache 2,075 4.0% 3 121
Cough 1,973 3.8% 4 78
Fatigue 1,876 3.6% 2 100
Incorrect dose administered 1,736 3.3% 6 66
Vomiting 1,408 2.7% 12 213
Nasal congestion 1,339 2.6% 0 29
Malaise 1,316 2.5% 4 79
Off label use 1,293 2.5% 55 190
Oropharyngeal pain 1,218 2.3% 0 35
Pyrexia 1,211 2.3% 4 68
Dizziness 1,183 2.3% 1 117
Taste disorder 1,067 2.1% 0 46
Therapeutic product effect incomplete 1,062 2.0% 2 35
Rhinorrhoea 1,060 2.0% 1 18
Symptom recurrence 990 1.9% 1 5

Who Reports NIRMATRELVIR\RITONAVIR Side Effects? Age & Gender Data

Gender: 63.9% female, 36.1% male. Average age: 60.4 years. Most reports from: US. View detailed demographics →

Is NIRMATRELVIR\RITONAVIR Getting Safer? Reports by Year

YearReportsDeathsHosp.
2001 1 0 0
2002 1 0 0
2009 1 0 1
2017 1 0 0
2018 3 0 2
2019 9 0 3
2020 12 0 4
2021 57 3 13
2022 21,697 158 1,104
2023 10,389 48 603
2024 5,223 31 191
2025 844 9 50

View full timeline →

What Is NIRMATRELVIR\RITONAVIR Used For?

IndicationReports
Covid-19 treatment 44,763
Covid-19 4,587
Sars-cov-2 test positive 292
Product used for unknown indication 291
Coronavirus infection 220
Covid-19 immunisation 108
Antiviral treatment 74
Covid-19 pneumonia 60
Upper respiratory tract infection 58
Post-acute covid-19 syndrome 49

NIRMATRELVIR\RITONAVIR vs Alternatives: Which Is Safer?

NIRMATRELVIR\RITONAVIR vs NIROGACESTAT NIRMATRELVIR\RITONAVIR vs NIROGACESTAT HYDROBROMIDE NIRMATRELVIR\RITONAVIR vs NIRSEVIMAB NIRMATRELVIR\RITONAVIR vs NIRSEVIMAB-ALIP NIRMATRELVIR\RITONAVIR vs NITAZOXANIDE NIRMATRELVIR\RITONAVIR vs NITISINONE NIRMATRELVIR\RITONAVIR vs NITRAZEPAM NIRMATRELVIR\RITONAVIR vs NITRENDIPINE NIRMATRELVIR\RITONAVIR vs NITRIC NIRMATRELVIR\RITONAVIR vs NITROFURANTOIN

Official FDA Label for NIRMATRELVIR\RITONAVIR

Official prescribing information from the FDA-approved drug label.