NITISINONE for Alkaptonuria: Side Effects & Safety Data
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There are 92 adverse event reports in the FDA FAERS database where NITISINONE was used for Alkaptonuria.
Most Reported Side Effects for NITISINONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Amino acid level increased | 118 | 15.7% | 2 | 18 |
| Liver transplant | 62 | 8.2% | 5 | 32 |
| Hepatocellular carcinoma | 58 | 7.7% | 17 | 18 |
| Cataract | 47 | 6.3% | 0 | 0 |
| Off label use | 41 | 5.5% | 3 | 7 |
| Alpha 1 foetoprotein increased | 39 | 5.2% | 5 | 10 |
| Lenticular opacities | 34 | 4.5% | 0 | 0 |
| Vomiting | 32 | 4.3% | 4 | 23 |
| Succinylacetone increased | 31 | 4.1% | 2 | 9 |
| Treatment noncompliance | 30 | 4.0% | 0 | 15 |
| Death | 29 | 3.9% | 29 | 2 |
| Abdominal pain | 26 | 3.5% | 1 | 21 |
| Hepatic failure | 25 | 3.3% | 13 | 11 |
| Seizure | 24 | 3.2% | 8 | 8 |
| Product dose omission issue | 18 | 2.4% | 2 | 7 |