NITRAZEPAM: 1,165 Adverse Event Reports & Safety Profile
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1,165
Total FAERS Reports
365 (31.3%)
Deaths Reported
466
Hospitalizations
1,165
As Primary/Secondary Suspect
92
Life-Threatening
34
Disabilities
First Report: 1971 · Latest Report: 20250313
What Are the Most Common NITRAZEPAM Side Effects?
#1 Most Reported
Toxicity to various agents
228 reports (19.6%)
#2 Most Reported
Suicide attempt
105 reports (9.0%)
#3 Most Reported
Intentional overdose
102 reports (8.8%)
All NITRAZEPAM Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Toxicity to various agents | 228 | 19.6% | 170 | 53 |
| Suicide attempt | 105 | 9.0% | 4 | 44 |
| Chest discomfort | 102 | 8.8% | 80 | 22 |
| Intentional overdose | 102 | 8.8% | 14 | 51 |
| Drug ineffective | 101 | 8.7% | 5 | 31 |
| Fall | 95 | 8.2% | 15 | 73 |
| Somnolence | 93 | 8.0% | 12 | 28 |
| Drug abuse | 86 | 7.4% | 42 | 34 |
| Overdose | 74 | 6.4% | 33 | 47 |
| Off label use | 70 | 6.0% | 7 | 28 |
| Fatigue | 59 | 5.1% | 1 | 26 |
| Loss of consciousness | 53 | 4.6% | 16 | 36 |
| Pulmonary oedema | 50 | 4.3% | 18 | 33 |
| Weight increased | 48 | 4.1% | 0 | 25 |
| Dyspnoea | 47 | 4.0% | 1 | 25 |
| Myocardial infarction | 43 | 3.7% | 13 | 29 |
| Tachycardia | 41 | 3.5% | 0 | 34 |
| Asthma | 40 | 3.4% | 0 | 38 |
| Dizziness | 40 | 3.4% | 1 | 26 |
| Memory impairment | 39 | 3.4% | 0 | 7 |
Who Reports NITRAZEPAM Side Effects? Age & Gender Data
Gender: 54.1% female, 45.9% male. Average age: 51.2 years. Most reports from: JP. View detailed demographics →
Is NITRAZEPAM Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 0 |
| 2006 | 2 | 2 | 0 |
| 2007 | 2 | 1 | 0 |
| 2008 | 6 | 0 | 0 |
| 2009 | 6 | 1 | 4 |
| 2010 | 5 | 0 | 4 |
| 2011 | 4 | 3 | 2 |
| 2012 | 8 | 1 | 5 |
| 2013 | 10 | 2 | 3 |
| 2014 | 34 | 13 | 16 |
| 2015 | 23 | 7 | 15 |
| 2016 | 39 | 4 | 31 |
| 2017 | 40 | 10 | 17 |
| 2018 | 79 | 7 | 70 |
| 2019 | 33 | 15 | 13 |
| 2020 | 54 | 6 | 24 |
| 2021 | 40 | 6 | 21 |
| 2022 | 33 | 10 | 18 |
| 2023 | 4 | 0 | 1 |
| 2024 | 15 | 0 | 3 |
| 2025 | 3 | 0 | 1 |
What Is NITRAZEPAM Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 573 |
| Insomnia | 86 |
| Epilepsy | 41 |
| Sleep disorder | 37 |
| Depression | 32 |
| Seizure | 22 |
| Myoclonic epilepsy | 17 |
| Pain | 17 |
| Lennox-gastaut syndrome | 16 |
| Partial seizures | 15 |
NITRAZEPAM vs Alternatives: Which Is Safer?
NITRAZEPAM vs NITRENDIPINE
NITRAZEPAM vs NITRIC
NITRAZEPAM vs NITROFURANTOIN
NITRAZEPAM vs NITROFURANTOIN\NITROFURANTOIN
NITRAZEPAM vs NITROFURAZONE
NITRAZEPAM vs NITROGLYCERIN
NITRAZEPAM vs NITROUS
NITRAZEPAM vs NITROUS\OXYGEN
NITRAZEPAM vs NIVOLUMAB
NITRAZEPAM vs NIVOLUMAB\RELATLIMAB-RMBW
Official FDA Label for NITRAZEPAM
Official prescribing information from the FDA-approved drug label.