NITROUS: 1,046 Adverse Event Reports & Safety Profile

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1,046

Total FAERS Reports

129 (12.3%)

Deaths Reported

440

Hospitalizations

1,046

As Primary/Secondary Suspect

Life-Threatening

Disabilities

FULLERTON WELDING SUPPLY

Manufacturer

Prescription

Status

Active Ingredient: NITROUS OXIDE · Route: RESPIRATORY (INHALATION) · Manufacturer: FULLERTON WELDING SUPPLY · FDA Application: 205704 · HUMAN PRESCRIPTION DRUG · FDA Label: Available

First Report: 19740706 · Latest Report: 20250811

What Are the Most Common NITROUS Side Effects?

#1 Most Reported

Drug abuse

141 reports (13.5%)

#2 Most Reported

Subacute combined cord degeneration

82 reports (7.8%)

#3 Most Reported

Substance use

47 reports (4.5%)

All NITROUS Side Effects by Frequency

Side Effect	Reports	% of Total	Deaths	Hosp.
Drug abuse	141	13.5%	19	71
Subacute combined cord degeneration	82	7.8%	1	50
Substance use	47	4.5%	3	20
Toxicity to various agents	46	4.4%	10	16
Vitamin b12 deficiency	44	4.2%	0	28
Drug dependence	42	4.0%	1	21
Choroidal infarction	40	3.8%	0	0
Paraesthesia	38	3.6%	0	25
Cardiac arrest	36	3.4%	26	7
Off label use	34	3.3%	0	5
Myelopathy	33	3.2%	0	23
Intentional product misuse	32	3.1%	1	6
Bradycardia	28	2.7%	3	6
Vomiting	28	2.7%	0	6
Drug interaction	27	2.6%	8	9
Drug ineffective	25	2.4%	2	16
Hypoxia	25	2.4%	5	6
Anaesthetic complication neurological	24	2.3%	0	0
Muscular weakness	24	2.3%	0	21
Hyperthermia malignant	23	2.2%	4	12

Who Reports NITROUS Side Effects? Age & Gender Data

Gender: 44.1% female, 55.9% male. Average age: 27.4 years. Most reports from: US. View detailed demographics →

Is NITROUS Getting Safer? Reports by Year

Year	Reports	Deaths	Hosp.
2001	2	2	0
2005	4	0	0
2006	1	0	0
2008	4	4	0
2009	2	0	1
2010	2	0	2
2011	2	0	1
2013	8	2	1
2014	11	5	4
2015	16	3	10
2016	8	3	2
2017	17	3	4
2018	21	2	8
2019	11	0	4
2020	5	2	2
2021	35	8	16
2022	25	2	15
2023	20	1	7
2024	14	1	9
2025	17	1	11

View full timeline →

What Is NITROUS Used For?

Indication	Reports
Product used for unknown indication	273
General anaesthesia	111
Drug abuse	107
Anaesthesia	88
Maintenance of anaesthesia	67
Induction of anaesthesia	65
Substance use	44
Analgesic therapy	31
Substance abuse	17
Sedative therapy	16

NITROUS vs Alternatives: Which Is Safer?

NITROUS vs NITROUS\OXYGEN NITROUS vs NIVOLUMAB NITROUS vs NIVOLUMAB\RELATLIMAB-RMBW NITROUS vs NIZATIDINE NITROUS vs NOMEGESTROL NITROUS vs NORDAZEPAM NITROUS vs NOREPINEPHRINE NITROUS vs NOREPINEPHRINE\NOREPINEPHRINE NITROUS vs NORETHINDRONE NITROUS vs NORFLOXACIN

Official FDA Label for NITROUS

Official prescribing information from the FDA-approved drug label.