Does NIVOLUMAB Cause Melaena? 129 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 129 reports of Melaena have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.2% of all adverse event reports for NIVOLUMAB.
129
Reports of Melaena with NIVOLUMAB
0.2%
of all NIVOLUMAB reports
39
Deaths
82
Hospitalizations
How Dangerous Is Melaena From NIVOLUMAB?
Of the 129 reports, 39 (30.2%) resulted in death, 82 (63.6%) required hospitalization, and 14 (10.9%) were considered life-threatening.
Is Melaena Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 129 reports have been filed with the FAERS database.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Melaena?
ASPIRIN (2,001)
CLOPIDOGREL BISULFATE (1,547)
RIVAROXABAN (1,405)
APIXABAN (1,156)
WARFARIN (930)
IBUPROFEN (810)
DABIGATRAN ETEXILATE (700)
DICLOFENAC (576)
NAPROXEN (291)
FUROSEMIDE (272)
Which NIVOLUMAB Alternatives Have Lower Melaena Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE