Does PATISIRAN Cause Bradycardia? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Bradycardia have been filed in association with PATISIRAN (Onpattro). This represents 0.6% of all adverse event reports for PATISIRAN.
15
Reports of Bradycardia with PATISIRAN
0.6%
of all PATISIRAN reports
3
Deaths
9
Hospitalizations
How Dangerous Is Bradycardia From PATISIRAN?
Of the 15 reports, 3 (20.0%) resulted in death, 9 (60.0%) required hospitalization, and 1 (6.7%) were considered life-threatening.
Is Bradycardia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PATISIRAN. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does PATISIRAN Cause?
Death (250)
Product dose omission issue (175)
Fatigue (165)
Infusion related reaction (134)
Hospitalisation (127)
Asthenia (108)
Fall (107)
Intentional dose omission (107)
Cardiac failure (95)
Dyspnoea (87)
What Other Drugs Cause Bradycardia?
BISOPROLOL (2,535)
METOPROLOL (2,024)
AMLODIPINE (1,840)
AMIODARONE (1,261)
FUROSEMIDE (1,032)
ATENOLOL (942)
PROPRANOLOL (934)
DIGOXIN (896)
CARVEDILOL (861)
FINGOLIMOD (861)
Which PATISIRAN Alternatives Have Lower Bradycardia Risk?
PATISIRAN vs PAXIL
PATISIRAN vs PAZOPANIB
PATISIRAN vs PEANUT
PATISIRAN vs PEG INTERFERON
PATISIRAN vs PEG-INTERFERON ALFA 2A