Does PEGLOTICASE Cause Hyperkalaemia? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Hyperkalaemia have been filed in association with PEGLOTICASE (Krystexxa). This represents 0.2% of all adverse event reports for PEGLOTICASE.
5
Reports of Hyperkalaemia with PEGLOTICASE
0.2%
of all PEGLOTICASE reports
2
Deaths
4
Hospitalizations
How Dangerous Is Hyperkalaemia From PEGLOTICASE?
Of the 5 reports, 2 (40.0%) resulted in death, 4 (80.0%) required hospitalization, and 1 (20.0%) were considered life-threatening.
Is Hyperkalaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGLOTICASE. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does PEGLOTICASE Cause?
Gout (487)
Blood uric acid increased (359)
Infusion related reaction (284)
Therapeutic response decreased (186)
Dyspnoea (153)
Urticaria (133)
Drug ineffective (131)
Nausea (119)
Pruritus (118)
Rash (116)
What Other Drugs Cause Hyperkalaemia?
METFORMIN (2,565)
SPIRONOLACTONE (2,518)
FUROSEMIDE (2,035)
RAMIPRIL (1,383)
SACUBITRIL\VALSARTAN (1,192)
SULFAMETHOXAZOLE\TRIMETHOPRIM (1,036)
LISINOPRIL (948)
POTASSIUM (944)
BISOPROLOL (850)
TACROLIMUS (713)
Which PEGLOTICASE Alternatives Have Lower Hyperkalaemia Risk?
PEGLOTICASE vs PEGUNIGALSIDASE ALFA-IWXJ
PEGLOTICASE vs PEGVALIASE-PQPZ
PEGLOTICASE vs PEGVISOMANT
PEGLOTICASE vs PEGZEREPOETIN ALFA
PEGLOTICASE vs PEMBROLIZUMAB