PEGUNIGALSIDASE ALFA-IWXJ: 202 Adverse Event Reports & Safety Profile
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202
Total FAERS Reports
3 (1.5%)
Deaths Reported
43
Hospitalizations
202
As Primary/Secondary Suspect
2
Life-Threatening
2
Disabilities
Prescription
Status
FDA Application: 761161 ·
First Report: 20221101 · Latest Report: 20250906
What Are the Most Common PEGUNIGALSIDASE ALFA-IWXJ Side Effects?
#1 Most Reported
Fatigue
30 reports (14.9%)
#2 Most Reported
Off label use
25 reports (12.4%)
#3 Most Reported
Nausea
16 reports (7.9%)
All PEGUNIGALSIDASE ALFA-IWXJ Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Fatigue | 30 | 14.9% | 0 | 1 |
| Off label use | 25 | 12.4% | 1 | 5 |
| Nausea | 16 | 7.9% | 0 | 1 |
| Ill-defined disorder | 13 | 6.4% | 1 | 13 |
| Asthenia | 11 | 5.5% | 1 | 3 |
| Chills | 11 | 5.5% | 0 | 3 |
| Infusion related reaction | 10 | 5.0% | 0 | 2 |
| Pain | 10 | 5.0% | 0 | 3 |
| Product dose omission issue | 10 | 5.0% | 0 | 3 |
| Pyrexia | 10 | 5.0% | 0 | 0 |
| Vomiting | 10 | 5.0% | 0 | 1 |
| Burning sensation | 8 | 4.0% | 0 | 0 |
| Chest pain | 8 | 4.0% | 0 | 2 |
| Pain in extremity | 7 | 3.5% | 0 | 2 |
| Urticaria | 7 | 3.5% | 0 | 0 |
| Abdominal pain | 6 | 3.0% | 0 | 2 |
| Gastrointestinal disorder | 6 | 3.0% | 0 | 0 |
| Headache | 6 | 3.0% | 0 | 0 |
| Abdominal pain upper | 5 | 2.5% | 0 | 1 |
| Condition aggravated | 5 | 2.5% | 0 | 1 |
Who Reports PEGUNIGALSIDASE ALFA-IWXJ Side Effects? Age & Gender Data
Gender: 41.4% female, 58.6% male. Average age: 40.4 years. Most reports from: US. View detailed demographics →
Is PEGUNIGALSIDASE ALFA-IWXJ Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2022 | 1 | 0 | 0 |
| 2023 | 34 | 2 | 14 |
| 2024 | 73 | 1 | 16 |
| 2025 | 48 | 0 | 10 |
What Is PEGUNIGALSIDASE ALFA-IWXJ Used For?
| Indication | Reports |
|---|---|
| Fabry's disease | 161 |
| Product used for unknown indication | 40 |
PEGUNIGALSIDASE ALFA-IWXJ vs Alternatives: Which Is Safer?
PEGUNIGALSIDASE ALFA-IWXJ vs PEGVALIASE-PQPZ
PEGUNIGALSIDASE ALFA-IWXJ vs PEGVISOMANT
PEGUNIGALSIDASE ALFA-IWXJ vs PEGZEREPOETIN ALFA
PEGUNIGALSIDASE ALFA-IWXJ vs PEMBROLIZUMAB
PEGUNIGALSIDASE ALFA-IWXJ vs PEMETREXED
PEGUNIGALSIDASE ALFA-IWXJ vs PEMIGATINIB
PEGUNIGALSIDASE ALFA-IWXJ vs PENICILLAMINE
PEGUNIGALSIDASE ALFA-IWXJ vs PENICILLIN
PEGUNIGALSIDASE ALFA-IWXJ vs PENICILLIN G
PEGUNIGALSIDASE ALFA-IWXJ vs PENICILLIN G BENZATHINE
Official FDA Label for PEGUNIGALSIDASE ALFA-IWXJ
Official prescribing information from the FDA-approved drug label.