Does PEMBROLIZUMAB Cause Aphasia? 90 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 90 reports of Aphasia have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
90
Reports of Aphasia with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
15
Deaths
62
Hospitalizations
How Dangerous Is Aphasia From PEMBROLIZUMAB?
Of the 90 reports, 15 (16.7%) resulted in death, 62 (68.9%) required hospitalization, and 15 (16.7%) were considered life-threatening.
Is Aphasia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 90 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Aphasia?
METHOTREXATE (509)
ASPIRIN (468)
ADALIMUMAB (461)
DIMETHYL (438)
NATALIZUMAB (433)
METFORMIN (393)
AMLODIPINE (385)
ATORVASTATIN (356)
CARBIDOPA\LEVODOPA (356)
INTERFERON BETA-1A (343)
Which PEMBROLIZUMAB Alternatives Have Lower Aphasia Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G