Does PEMBROLIZUMAB Cause Blindness? 70 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Blindness have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
70
Reports of Blindness with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
18
Deaths
25
Hospitalizations
How Dangerous Is Blindness From PEMBROLIZUMAB?
Of the 70 reports, 18 (25.7%) resulted in death, 25 (35.7%) required hospitalization, and 7 (10.0%) were considered life-threatening.
Is Blindness Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 70 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Blindness?
ADALIMUMAB (1,599)
AFLIBERCEPT (1,337)
BEVACIZUMAB (847)
INSULIN GLARGINE (837)
APIXABAN (789)
INSULIN LISPRO (760)
RANIBIZUMAB (760)
ETANERCEPT (669)
PREGABALIN (646)
ESOMEPRAZOLE (617)
Which PEMBROLIZUMAB Alternatives Have Lower Blindness Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G