Does PEMBROLIZUMAB Cause Cardiomyopathy? 174 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 174 reports of Cardiomyopathy have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
174
Reports of Cardiomyopathy with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
30
Deaths
98
Hospitalizations
How Dangerous Is Cardiomyopathy From PEMBROLIZUMAB?
Of the 174 reports, 30 (17.2%) resulted in death, 98 (56.3%) required hospitalization, and 29 (16.7%) were considered life-threatening.
Is Cardiomyopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 174 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Cardiomyopathy?
DOXORUBICIN (820)
CYCLOPHOSPHAMIDE (581)
SACUBITRIL\VALSARTAN (444)
CLOZAPINE (404)
PREDNISONE (379)
RITUXIMAB (379)
ROSIGLITAZONE (374)
VINCRISTINE (326)
TRASTUZUMAB (292)
HYDROXYCHLOROQUINE (231)
Which PEMBROLIZUMAB Alternatives Have Lower Cardiomyopathy Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G