Does PEMBROLIZUMAB Cause Diplopia? 135 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 135 reports of Diplopia have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
135
Reports of Diplopia with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
24
Deaths
76
Hospitalizations
How Dangerous Is Diplopia From PEMBROLIZUMAB?
Of the 135 reports, 24 (17.8%) resulted in death, 76 (56.3%) required hospitalization, and 13 (9.6%) were considered life-threatening.
Is Diplopia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 135 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Diplopia?
ESOMEPRAZOLE (585)
SIMVASTATIN (560)
PREGABALIN (556)
HYDROCHLOROTHIAZIDE (544)
BISOPROLOL (541)
ADALIMUMAB (531)
FINGOLIMOD (505)
LEVOTHYROXINE (473)
APIXABAN (471)
ATORVASTATIN (396)
Which PEMBROLIZUMAB Alternatives Have Lower Diplopia Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G