Does PEMBROLIZUMAB Cause Endocarditis? 52 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 52 reports of Endocarditis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
52
Reports of Endocarditis with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
6
Deaths
37
Hospitalizations
How Dangerous Is Endocarditis From PEMBROLIZUMAB?
Of the 52 reports, 6 (11.5%) resulted in death, 37 (71.2%) required hospitalization, and 10 (19.2%) were considered life-threatening.
Is Endocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 52 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Endocarditis?
PREDNISONE (224)
PREDNISOLONE (176)
METHOTREXATE (170)
MYCOPHENOLATE MOFETIL (167)
DEXAMETHASONE (156)
TACROLIMUS (153)
RITUXIMAB (128)
CYCLOPHOSPHAMIDE (125)
VANCOMYCIN (110)
TOCILIZUMAB (104)
Which PEMBROLIZUMAB Alternatives Have Lower Endocarditis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G