Does PEMBROLIZUMAB Cause Fistula? 75 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 75 reports of Fistula have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
75
Reports of Fistula with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
14
Deaths
47
Hospitalizations
How Dangerous Is Fistula From PEMBROLIZUMAB?
Of the 75 reports, 14 (18.7%) resulted in death, 47 (62.7%) required hospitalization, and 2 (2.7%) were considered life-threatening.
Is Fistula Listed in the Official Label?
Yes, Fistula is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Fistula?
ADALIMUMAB (1,882)
INFLIXIMAB (1,170)
INFLIXIMAB-DYYB (866)
VEDOLIZUMAB (589)
USTEKINUMAB (316)
BEVACIZUMAB (215)
METHOTREXATE (197)
RISANKIZUMAB-RZAA (190)
ZOLEDRONIC ACID (189)
UPADACITINIB (124)
Which PEMBROLIZUMAB Alternatives Have Lower Fistula Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G