Does PEMBROLIZUMAB Cause Fracture? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Fracture have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.0% of all adverse event reports for PEMBROLIZUMAB.
36
Reports of Fracture with PEMBROLIZUMAB
0.0%
of all PEMBROLIZUMAB reports
5
Deaths
28
Hospitalizations
How Dangerous Is Fracture From PEMBROLIZUMAB?
Of the 36 reports, 5 (13.9%) resulted in death, 28 (77.8%) required hospitalization, and 1 (2.8%) were considered life-threatening.
Is Fracture Listed in the Official Label?
Yes, Fracture is listed as a known adverse reaction in the official FDA drug label for PEMBROLIZUMAB.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Fracture?
DENOSUMAB (1,392)
EMTRICITABINE\TENOFOVIR DISOPROXIL (1,296)
TENOFOVIR DISOPROXIL (783)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (734)
ROMOSOZUMAB-AQQG (612)
ABATACEPT (543)
TERIPARATIDE (516)
LENALIDOMIDE (463)
ETANERCEPT (384)
METHOTREXATE (319)
Which PEMBROLIZUMAB Alternatives Have Lower Fracture Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G