Does PEMBROLIZUMAB Cause Ileus? 177 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 177 reports of Ileus have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
177
Reports of Ileus with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
46
Deaths
132
Hospitalizations
How Dangerous Is Ileus From PEMBROLIZUMAB?
Of the 177 reports, 46 (26.0%) resulted in death, 132 (74.6%) required hospitalization, and 24 (13.6%) were considered life-threatening.
Is Ileus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 177 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Ileus?
SEMAGLUTIDE (543)
ADALIMUMAB (377)
BEVACIZUMAB (333)
DEXAMETHASONE (258)
VINCRISTINE (229)
DOXORUBICIN (228)
CLOZAPINE (224)
RITUXIMAB (212)
PACLITAXEL (211)
CARBOPLATIN (208)
Which PEMBROLIZUMAB Alternatives Have Lower Ileus Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G