Does PEMBROLIZUMAB Cause Jaundice? 132 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 132 reports of Jaundice have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.2% of all adverse event reports for PEMBROLIZUMAB.
132
Reports of Jaundice with PEMBROLIZUMAB
0.2%
of all PEMBROLIZUMAB reports
30
Deaths
101
Hospitalizations
How Dangerous Is Jaundice From PEMBROLIZUMAB?
Of the 132 reports, 30 (22.7%) resulted in death, 101 (76.5%) required hospitalization, and 19 (14.4%) were considered life-threatening.
Is Jaundice Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 132 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Jaundice?
RIBAVIRIN (647)
ACETAMINOPHEN (553)
ATORVASTATIN (518)
RIFAMPIN (336)
IBUPROFEN (334)
ECULIZUMAB (333)
METHOTREXATE (295)
OMBITASVIR\PARITAPREVIR\RITONAVIR (279)
AMOXICILLIN\CLAVULANATE (272)
DASABUVIR (247)
Which PEMBROLIZUMAB Alternatives Have Lower Jaundice Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G