Does PEMBROLIZUMAB Cause Leukocytosis? 86 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 86 reports of Leukocytosis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
86
Reports of Leukocytosis with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
31
Deaths
67
Hospitalizations
How Dangerous Is Leukocytosis From PEMBROLIZUMAB?
Of the 86 reports, 31 (36.0%) resulted in death, 67 (77.9%) required hospitalization, and 12 (14.0%) were considered life-threatening.
Is Leukocytosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 86 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Leukocytosis?
CLOZAPINE (1,460)
PREDNISONE (419)
ACETAMINOPHEN (356)
METFORMIN (345)
RUXOLITINIB (320)
RITUXIMAB (272)
METHYLPREDNISOLONE (252)
AMLODIPINE (250)
IBRUTINIB (243)
DEXAMETHASONE (235)
Which PEMBROLIZUMAB Alternatives Have Lower Leukocytosis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G