Does PEMBROLIZUMAB Cause Optic neuritis? 100 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 100 reports of Optic neuritis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
100
Reports of Optic neuritis with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
6
Deaths
35
Hospitalizations
How Dangerous Is Optic neuritis From PEMBROLIZUMAB?
Of the 100 reports, 6 (6.0%) resulted in death, 35 (35.0%) required hospitalization, and 3 (3.0%) were considered life-threatening.
Is Optic neuritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 100 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Optic neuritis?
FINGOLIMOD (619)
INTERFERON BETA-1A (422)
DIMETHYL (373)
NATALIZUMAB (272)
OCRELIZUMAB (236)
ADALIMUMAB (229)
TERIFLUNOMIDE (225)
GLATIRAMER (196)
OFATUMUMAB (185)
RITUXIMAB (164)
Which PEMBROLIZUMAB Alternatives Have Lower Optic neuritis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G