Does PEMBROLIZUMAB Cause Paralysis? 54 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 54 reports of Paralysis have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
54
Reports of Paralysis with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
3
Deaths
29
Hospitalizations
How Dangerous Is Paralysis From PEMBROLIZUMAB?
Of the 54 reports, 3 (5.6%) resulted in death, 29 (53.7%) required hospitalization, and 11 (20.4%) were considered life-threatening.
Is Paralysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 54 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Paralysis?
ADALIMUMAB (275)
INTERFERON BETA-1A (181)
METHOTREXATE (181)
PREGABALIN (171)
RITUXIMAB (166)
ATORVASTATIN (160)
DIMETHYL (156)
FINGOLIMOD (145)
NATALIZUMAB (136)
ETANERCEPT (134)
Which PEMBROLIZUMAB Alternatives Have Lower Paralysis Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G