Does PEMBROLIZUMAB Cause Seizure? 319 Reports in FDA Database

Q: Does PEMBROLIZUMAB cause Seizure?

319 reports of Seizure have been filed with the FDA for PEMBROLIZUMAB, representing 0.4% of all PEMBROLIZUMAB adverse event reports.

Q: How dangerous is Seizure from PEMBROLIZUMAB?

Of 319 reports, 60 (18.8%) resulted in death and 200 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 319 reports of Seizure have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.4% of all adverse event reports for PEMBROLIZUMAB.

319

Reports of Seizure with PEMBROLIZUMAB

0.4%

of all PEMBROLIZUMAB reports

Deaths

200

Hospitalizations

How Dangerous Is Seizure From PEMBROLIZUMAB?

Of the 319 reports, 60 (18.8%) resulted in death, 200 (62.7%) required hospitalization, and 40 (12.5%) were considered life-threatening.

Is Seizure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 319 reports have been filed with the FAERS database.

What Other Side Effects Does PEMBROLIZUMAB Cause?

Malignant neoplasm progression (10,111) Death (4,744) Diarrhoea (4,251) Fatigue (3,833) Off label use (3,416) Product use in unapproved indication (3,191) Pyrexia (3,155) Rash (2,900) Nausea (2,670) Decreased appetite (2,486)

What Other Drugs Cause Seizure?

LEVETIRACETAM (9,961) CANNABIDIOL (4,980) LACOSAMIDE (4,585) LAMOTRIGINE (3,459) ADALIMUMAB (2,510) BRIVARACETAM (2,411) VIGABATRIN (2,289) CARBAMAZEPINE (2,262) PHENYTOIN (1,907) BUPROPION (1,894)

Which PEMBROLIZUMAB Alternatives Have Lower Seizure Risk?

PEMBROLIZUMAB vs PEMETREXED PEMBROLIZUMAB vs PEMIGATINIB PEMBROLIZUMAB vs PENICILLAMINE PEMBROLIZUMAB vs PENICILLIN PEMBROLIZUMAB vs PENICILLIN G

PEMBROLIZUMAB Full Profile All Seizure Reports All Drugs Causing Seizure PEMBROLIZUMAB Demographics