Does PEMBROLIZUMAB Cause Sinus bradycardia? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Sinus bradycardia have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.0% of all adverse event reports for PEMBROLIZUMAB.
25
Reports of Sinus bradycardia with PEMBROLIZUMAB
0.0%
of all PEMBROLIZUMAB reports
3
Deaths
20
Hospitalizations
How Dangerous Is Sinus bradycardia From PEMBROLIZUMAB?
Of the 25 reports, 3 (12.0%) resulted in death, 20 (80.0%) required hospitalization, and 8 (32.0%) were considered life-threatening.
Is Sinus bradycardia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Sinus bradycardia?
BISOPROLOL (479)
METOPROLOL (342)
AMLODIPINE (339)
AMIODARONE (282)
FINGOLIMOD (243)
ATENOLOL (222)
DONEPEZIL (194)
CARVEDILOL (184)
DIGOXIN (156)
OLANZAPINE (132)
Which PEMBROLIZUMAB Alternatives Have Lower Sinus bradycardia Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G